AustralieFrV1, Main, Exploration, bibRecord, 005F12

A multi-centre pathologist survey on pathological processing and regression grading of colorectal cancer resection specimens treated by neoadjuvant chemoradiation

Identifieur interne : 005F12 ( Main/Exploration ); précédent : 005F11; suivant : 005F13

A multi-centre pathologist survey on pathological processing and regression grading of colorectal cancer resection specimens treated by neoadjuvant chemoradiation

Auteurs : Runjan Chetty [Royaume-Uni] ; Pelvender Gill [Royaume-Uni] ; Dhirendra Govender [Afrique du Sud] ; Adrian Bateman [Royaume-Uni] ; HEE JIN CHANG [Corée du Sud] ; David Driman [Canada] ; Fraser Duthie [Royaume-Uni] ; Marisa Gomez [Espagne] ; Eleanor Jaynes [Royaume-Uni] ; CHEOK SOON LEE [Australie] ; Michael Locketz [Afrique du Sud] ; Claudia Mescoli [Italie] ; Corwyn Rowsell [Canada] ; Anne Rullier [France] ; Stefano Serra [Canada] ; Neil Shepherd [Royaume-Uni] ; Eva Szentgyorgyi [Canada] ; Rajkumar Vajpeyi [Canada] ; LAI MUN WANG [Royaume-Uni]

Source :

Virchows Archiv [ 0945-6317 ] ; 2012.

RBID : Pascal:12-0158054

Descripteurs français

Pascal (Inist)
- Cancer colorectal, Surveillance, Enquête, Résection chirurgicale, Régression, Grade histologique, Traitement associé, Traitement néoadjuvant, Anatomopathologie, Radiothérapie, Chimiothérapie.

English descriptors

KwdEn :
- Anatomic pathology, Chemotherapy, Colorectal cancer, Combined treatment, Histological grading, Neoadjuvant treatment, Radiotherapy, Regression, Surgical resection, Surveillance, Survey.

Abstract

To ascertain the approach and degree of consensus of pathologists in the handling and regression grading of colorectal cancer resection specimens treated with neoadjuvant chemoradiation, a ten-part questionnaire was circulated to 18 gastrointestinal pathologists in eight countries. The questions were specific and addressed pertinent issues related to colorectal cancer with neoadjuvant chemoradiation. There is a lack of consensus on how to handle the specimen, number of sections taken, correlation with pre-and post-operative radiological imaging, and especially, regression grading schema employed. Consensus in the form of guidelines is required so that the pathological assessment of these specimens will provide clinically relevant information for patient management, irrespective of location.

Affiliations:

Afrique du Sud, Australie, Canada, Corée du Sud, Espagne, France, Italie, Royaume-Uni
Angleterre, Grand Londres, Nouvelle-Galles du Sud, Ontario, Oxfordshire
Londres, Oxford, Sydney, Toronto
Université d'Oxford, Université de Toronto

Links toward previous steps (curation, corpus...)

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to stream PascalFrancis, to step Curation: 004A18
to stream PascalFrancis, to step Checkpoint: 001408
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Le document en format XML

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<author><name sortKey="Serra, Stefano" sort="Serra, Stefano" uniqKey="Serra S" first="Stefano" last="Serra">Stefano Serra</name>
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<author><name sortKey="Vajpeyi, Rajkumar" sort="Vajpeyi, Rajkumar" uniqKey="Vajpeyi R" first="Rajkumar" last="Vajpeyi">Rajkumar Vajpeyi</name>
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<author><name sortKey="Lai Mun Wang" sort="Lai Mun Wang" uniqKey="Lai Mun Wang" last="Lai Mun Wang">LAI MUN WANG</name>
<affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Department of Cellular Pathology/Biomedical Research Centre/ Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital and University of Oxford</s1>
<s2>Oxford</s2>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">A multi-centre pathologist survey on pathological processing and regression grading of colorectal cancer resection specimens treated by neoadjuvant chemoradiation</title>
<author><name sortKey="Chetty, Runjan" sort="Chetty, Runjan" uniqKey="Chetty R" first="Runjan" last="Chetty">Runjan Chetty</name>
<affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Department of Cellular Pathology/Biomedical Research Centre/ Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital and University of Oxford</s1>
<s2>Oxford</s2>
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<author><name sortKey="Gill, Pelvender" sort="Gill, Pelvender" uniqKey="Gill P" first="Pelvender" last="Gill">Pelvender Gill</name>
<affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Department of Cellular Pathology/Biomedical Research Centre/ Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital and University of Oxford</s1>
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<author><name sortKey="Govender, Dhirendra" sort="Govender, Dhirendra" uniqKey="Govender D" first="Dhirendra" last="Govender">Dhirendra Govender</name>
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<s2>Southampton</s2>
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<author><name sortKey="Hee Jin Chang" sort="Hee Jin Chang" uniqKey="Hee Jin Chang" last="Hee Jin Chang">HEE JIN CHANG</name>
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<author><name sortKey="Driman, David" sort="Driman, David" uniqKey="Driman D" first="David" last="Driman">David Driman</name>
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<author><name sortKey="Gomez, Marisa" sort="Gomez, Marisa" uniqKey="Gomez M" first="Marisa" last="Gomez">Marisa Gomez</name>
<affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Department of Pathology, Hospital de Navarra</s1>
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<author><name sortKey="Jaynes, Eleanor" sort="Jaynes, Eleanor" uniqKey="Jaynes E" first="Eleanor" last="Jaynes">Eleanor Jaynes</name>
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<s2>Southampton</s2>
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<author><name sortKey="Cheok Soon Lee" sort="Cheok Soon Lee" uniqKey="Cheok Soon Lee" last="Cheok Soon Lee">CHEOK SOON LEE</name>
<affiliation wicri:level="3"><inist:fA14 i1="08"><s1>Department of Pathology, Liverpool & Royal Prince Alfred Hospital, University of Western Sydney</s1>
<s2>Sydney</s2>
<s3>AUS</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Locketz, Michael" sort="Locketz, Michael" uniqKey="Locketz M" first="Michael" last="Locketz">Michael Locketz</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Division of Anatomical Pathology, University of Cape Town/ Groote Schuur Hospital</s1>
<s2>Cape Town</s2>
<s3>ZAF</s3>
<sZ>3 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>Afrique du Sud</country>
<wicri:noRegion>Cape Town</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mescoli, Claudia" sort="Mescoli, Claudia" uniqKey="Mescoli C" first="Claudia" last="Mescoli">Claudia Mescoli</name>
<affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Department of Diagnostic Sciences & Special Therapies, Pathology Unit, University of Padova</s1>
<s2>Padova</s2>
<s3>ITA</s3>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<wicri:noRegion>Padova</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rowsell, Corwyn" sort="Rowsell, Corwyn" uniqKey="Rowsell C" first="Corwyn" last="Rowsell">Corwyn Rowsell</name>
<affiliation wicri:level="4"><inist:fA14 i1="10"><s1>Department of Pathology, Sunnybrook Health Science Center/University of Toronto</s1>
<s2>Toronto</s2>
<s3>CAN</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
<orgName type="university">Université de Toronto</orgName>
</affiliation>
</author>
<author><name sortKey="Rullier, Anne" sort="Rullier, Anne" uniqKey="Rullier A" first="Anne" last="Rullier">Anne Rullier</name>
<affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Department of Pathology, CHU Bordeaux</s1>
<s3>FRA</s3>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>CHU Bordeaux</wicri:noRegion>
<wicri:noRegion>Department of Pathology, CHU Bordeaux</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Serra, Stefano" sort="Serra, Stefano" uniqKey="Serra S" first="Stefano" last="Serra">Stefano Serra</name>
<affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Department of Pathology, University Health Network/University of Toronto</s1>
<s2>Toronto</s2>
<s3>CAN</s3>
<sZ>15 aut.</sZ>
<sZ>17 aut.</sZ>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Toronto</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shepherd, Neil" sort="Shepherd, Neil" uniqKey="Shepherd N" first="Neil" last="Shepherd">Neil Shepherd</name>
<affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Gloucestershire Cellular Pathology Laboratory, Cheltenham General Hospital</s1>
<s2>Cheltenham</s2>
<s3>GBR</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>Cheltenham</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Szentgyorgyi, Eva" sort="Szentgyorgyi, Eva" uniqKey="Szentgyorgyi E" first="Eva" last="Szentgyorgyi">Eva Szentgyorgyi</name>
<affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Department of Pathology, University Health Network/University of Toronto</s1>
<s2>Toronto</s2>
<s3>CAN</s3>
<sZ>15 aut.</sZ>
<sZ>17 aut.</sZ>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Toronto</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vajpeyi, Rajkumar" sort="Vajpeyi, Rajkumar" uniqKey="Vajpeyi R" first="Rajkumar" last="Vajpeyi">Rajkumar Vajpeyi</name>
<affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Department of Pathology, University Health Network/University of Toronto</s1>
<s2>Toronto</s2>
<s3>CAN</s3>
<sZ>15 aut.</sZ>
<sZ>17 aut.</sZ>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Toronto</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lai Mun Wang" sort="Lai Mun Wang" uniqKey="Lai Mun Wang" last="Lai Mun Wang">LAI MUN WANG</name>
<affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Department of Cellular Pathology/Biomedical Research Centre/ Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital and University of Oxford</s1>
<s2>Oxford</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Virchows Archiv</title>
<title level="j" type="abbreviated">Virchows Arch.</title>
<idno type="ISSN">0945-6317</idno>
<imprint><date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Virchows Archiv</title>
<title level="j" type="abbreviated">Virchows Arch.</title>
<idno type="ISSN">0945-6317</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anatomic pathology</term>
<term>Chemotherapy</term>
<term>Colorectal cancer</term>
<term>Combined treatment</term>
<term>Histological grading</term>
<term>Neoadjuvant treatment</term>
<term>Radiotherapy</term>
<term>Regression</term>
<term>Surgical resection</term>
<term>Surveillance</term>
<term>Survey</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Cancer colorectal</term>
<term>Surveillance</term>
<term>Enquête</term>
<term>Résection chirurgicale</term>
<term>Régression</term>
<term>Grade histologique</term>
<term>Traitement associé</term>
<term>Traitement néoadjuvant</term>
<term>Anatomopathologie</term>
<term>Radiothérapie</term>
<term>Chimiothérapie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">To ascertain the approach and degree of consensus of pathologists in the handling and regression grading of colorectal cancer resection specimens treated with neoadjuvant chemoradiation, a ten-part questionnaire was circulated to 18 gastrointestinal pathologists in eight countries. The questions were specific and addressed pertinent issues related to colorectal cancer with neoadjuvant chemoradiation. There is a lack of consensus on how to handle the specimen, number of sections taken, correlation with pre-and post-operative radiological imaging, and especially, regression grading schema employed. Consensus in the form of guidelines is required so that the pathological assessment of these specimens will provide clinically relevant information for patient management, irrespective of location.</div>
</front>
</TEI>
<affiliations><list><country><li>Afrique du Sud</li>
<li>Australie</li>
<li>Canada</li>
<li>Corée du Sud</li>
<li>Espagne</li>
<li>France</li>
<li>Italie</li>
<li>Royaume-Uni</li>
</country>
<region><li>Angleterre</li>
<li>Grand Londres</li>
<li>Nouvelle-Galles du Sud</li>
<li>Ontario</li>
<li>Oxfordshire</li>
</region>
<settlement><li>Londres</li>
<li>Oxford</li>
<li>Sydney</li>
<li>Toronto</li>
</settlement>
<orgName><li>Université d'Oxford</li>
<li>Université de Toronto</li>
</orgName>
</list>
<tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Chetty, Runjan" sort="Chetty, Runjan" uniqKey="Chetty R" first="Runjan" last="Chetty">Runjan Chetty</name>
</region>
<name sortKey="Bateman, Adrian" sort="Bateman, Adrian" uniqKey="Bateman A" first="Adrian" last="Bateman">Adrian Bateman</name>
<name sortKey="Duthie, Fraser" sort="Duthie, Fraser" uniqKey="Duthie F" first="Fraser" last="Duthie">Fraser Duthie</name>
<name sortKey="Gill, Pelvender" sort="Gill, Pelvender" uniqKey="Gill P" first="Pelvender" last="Gill">Pelvender Gill</name>
<name sortKey="Jaynes, Eleanor" sort="Jaynes, Eleanor" uniqKey="Jaynes E" first="Eleanor" last="Jaynes">Eleanor Jaynes</name>
<name sortKey="Lai Mun Wang" sort="Lai Mun Wang" uniqKey="Lai Mun Wang" last="Lai Mun Wang">LAI MUN WANG</name>
<name sortKey="Shepherd, Neil" sort="Shepherd, Neil" uniqKey="Shepherd N" first="Neil" last="Shepherd">Neil Shepherd</name>
</country>
<country name="Afrique du Sud"><noRegion><name sortKey="Govender, Dhirendra" sort="Govender, Dhirendra" uniqKey="Govender D" first="Dhirendra" last="Govender">Dhirendra Govender</name>
</noRegion>
<name sortKey="Locketz, Michael" sort="Locketz, Michael" uniqKey="Locketz M" first="Michael" last="Locketz">Michael Locketz</name>
</country>
<country name="Corée du Sud"><noRegion><name sortKey="Hee Jin Chang" sort="Hee Jin Chang" uniqKey="Hee Jin Chang" last="Hee Jin Chang">HEE JIN CHANG</name>
</noRegion>
</country>
<country name="Canada"><region name="Angleterre"><name sortKey="Driman, David" sort="Driman, David" uniqKey="Driman D" first="David" last="Driman">David Driman</name>
</region>
<name sortKey="Rowsell, Corwyn" sort="Rowsell, Corwyn" uniqKey="Rowsell C" first="Corwyn" last="Rowsell">Corwyn Rowsell</name>
<name sortKey="Serra, Stefano" sort="Serra, Stefano" uniqKey="Serra S" first="Stefano" last="Serra">Stefano Serra</name>
<name sortKey="Szentgyorgyi, Eva" sort="Szentgyorgyi, Eva" uniqKey="Szentgyorgyi E" first="Eva" last="Szentgyorgyi">Eva Szentgyorgyi</name>
<name sortKey="Vajpeyi, Rajkumar" sort="Vajpeyi, Rajkumar" uniqKey="Vajpeyi R" first="Rajkumar" last="Vajpeyi">Rajkumar Vajpeyi</name>
</country>
<country name="Espagne"><noRegion><name sortKey="Gomez, Marisa" sort="Gomez, Marisa" uniqKey="Gomez M" first="Marisa" last="Gomez">Marisa Gomez</name>
</noRegion>
</country>
<country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Cheok Soon Lee" sort="Cheok Soon Lee" uniqKey="Cheok Soon Lee" last="Cheok Soon Lee">CHEOK SOON LEE</name>
</region>
</country>
<country name="Italie"><noRegion><name sortKey="Mescoli, Claudia" sort="Mescoli, Claudia" uniqKey="Mescoli C" first="Claudia" last="Mescoli">Claudia Mescoli</name>
</noRegion>
</country>
<country name="France"><noRegion><name sortKey="Rullier, Anne" sort="Rullier, Anne" uniqKey="Rullier A" first="Anne" last="Rullier">Anne Rullier</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

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	Serveur d'exploration sur les relations entre la France et l'Australie
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A multi-centre pathologist survey on pathological processing and regression grading of colorectal cancer resection specimens treated by neoadjuvant chemoradiation

A multi-centre pathologist survey on pathological processing and regression grading of colorectal cancer resection specimens treated by neoadjuvant chemoradiation

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